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Severe allergic reaction

Anaphylaxis is a sudden, life-threatening allergic reaction. Call for an ambulance at once, use an adrenaline auto-injector if there is one, and lay the person down with their legs raised. Do not let them stand or walk.

For everyone

3 minute read

In 60 seconds

  1. A severe allergic reaction (anaphylaxis) is a sudden, life-threatening reaction to something such as a food, an insect sting or a medicine. It usually starts within minutes and is always an emergency.
  2. Signs include swelling of the lips, mouth, tongue or throat, a tight throat, fast or noisy breathing, feeling faint or confused, and pale, blue or grey skin. An itchy rash may come with them.
  3. Call for an ambulance at once and say you think it is anaphylaxis. If the person has an adrenaline auto-injector, help them use it straight away and follow the instructions on the device. If there is no improvement after about 5 minutes, use a second one if there is one.
  4. Lay the person down with their legs raised. If breathing is difficult, let them sit up instead. Do not let them stand or walk, even if they feel better.
  5. Adrenaline is the first treatment. Do not give tablets or drinks to someone who is struggling to breathe. Everyone who has had anaphylaxis needs to be seen in hospital, because symptoms can come back.

What to do

  1. If the person has an adrenaline auto-injector (for example an EpiPen), help them use it straight away, or use it yourself. Follow the instructions printed on the device. The injection goes into the outer part of the thigh.
  2. Call for an ambulance, or ask someone to while you help. Say that you think it is anaphylaxis.
  3. Lay the person down and raise their legs. If breathing is difficult, let them sit up instead. If they are pregnant, lay them on their left side.
  4. Keep them in that position. Do not let them stand or walk, even if they start to feel better.
  5. If there is no improvement after about 5 minutes and there is a second auto-injector, use it.
  6. Keep watching their breathing and how they respond until the ambulance arrives. If they stop responding and are not breathing normally, start CPR, as in the hands-only CPR guide.
  7. Stay with them. Tell the ambulance team what you think caused the reaction and whether an auto-injector was used.

Adrenaline auto-injectors are not easy to get in India, so many people who are at risk will not have one. If there is none, do not wait: call for an ambulance and keep the person lying down.

What not to do:

  • Do not let the person stand or walk, even if they feel better.
  • Do not wait to see whether it passes before calling for help or using the auto-injector.
  • Do not give tablets, medicines or drinks to someone who is struggling to breathe.
  • Do not put a pillow under the head of someone who is having trouble breathing.

Spotting a severe allergic reaction

Anaphylaxis usually starts within minutes of contact with the trigger. Common triggers are foods such as nuts, milk, eggs, fish and sesame, insect stings, some medicines such as certain and painkillers, and latex. Sometimes no cause is found.

Signs of a severe reaction:

  • swelling of the lips, mouth, tongue or throat, a tight throat or trouble swallowing
  • fast, difficult or noisy breathing, wheezing or coughing
  • feeling faint, dizzy, confused or agitated, or collapsing
  • pale, blue or grey skin, lips or tongue, or cold skin
  • a child who is limp, floppy or not responding as usual

An itchy, raised rash, watery eyes, swelling of the face or hands, tummy pain or vomiting can be signs of a milder reaction. Watch closely, and treat it as anaphylaxis if any of the signs above appear.

When to call for an ambulance

Everyone who has had anaphylaxis needs to be seen in hospital, even if the auto-injector has worked, because symptoms can come back after they first improve. People are usually watched for several hours.

If you or your child is at risk

  • Avoid known triggers, and check food labels carefully.
  • Ask your doctor for an emergency plan. If you are prescribed auto-injectors, carry two with you at all times, check their expiry dates and keep them away from heat and the fridge.
  • Practise with a trainer injector, which has no needle or medicine, and teach family, friends and carers when and how to use yours.
  • Use the injector if you think it is anaphylaxis, even if the symptoms seem mild.

Myths and facts

Things people often say about this. Open each one to see what is true.

Myth“Give an antihistamine tablet and wait to see whether the swelling settles.”What is true?

Fact

Adrenaline is the first treatment for anaphylaxis, and an ambulance is needed. Do not give tablets or drinks to someone who is struggling to breathe, and do not wait to see whether it passes.

Myth“Once the person feels better, they can get up and walk around.”What is true?

Fact

The person should not stand or walk at any time, even if they feel better. Keep them lying down, or sitting up if breathing is difficult, until the ambulance team arrives.

Myth“Wait until you are completely sure it is anaphylaxis before using the auto-injector.”What is true?

Fact

The advice is to use the auto-injector if you think it is anaphylaxis, even if the symptoms seem mild, and to call for an ambulance.

Myth“If the injection works, there is no need to go to hospital.”What is true?

Fact

Anaphylaxis needs treatment in hospital. Symptoms can come back after they first improve, so people are watched for several hours.

Common questions

How is anaphylaxis different from an ordinary allergy?

A milder reaction may cause an itchy rash, watery eyes, swelling of the face or hands, tummy pain or vomiting. Anaphylaxis also affects breathing or the circulation, with signs such as a swollen tongue or throat, wheezing, confusion or collapse. It is an emergency.

What if the person has no auto-injector?

Call for an ambulance at once and lay the person down with their legs raised, or sitting up if breathing is difficult. Adrenaline and the other treatment are given by the medical team, so do not wait for it to pass.

When can I use a second auto-injector?

If the symptoms have not improved after about 5 minutes and there is a second auto-injector, use it. Say so when the ambulance team arrives.

Where does the injection go?

Follow the instructions printed on the device. Medical guidance places an adrenaline injection in the outer part of the thigh.

Please phone us

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