Overview
Hand, foot and mouth disease is a common viral infection of young children, although anyone can catch it. It is caused by a group of viruses and has nothing to do with the foot and mouth disease that affects cattle.
It is a mild illness in almost every child. Symptoms start about three to five days after catching the virus and are over in about 7 to 10 days. It spreads quickly in creches and playgroups, so several children in a class often get it at once.
Symptoms
The illness usually begins with a fever, a sore throat, a general feeling of being unwell and loss of appetite. A child may dribble more than usual, or refuse warm drinks.
A day or two later, small red spots appear on the tongue and inside the mouth. They blister and can be very sore, which is what makes eating and drinking difficult. A rash of flat or slightly raised red spots, sometimes with blisters, then appears on the palms and soles, and often on the buttocks, legs, arms and around the nappy area. The rash does not usually itch. On darker skin the spots can be harder to see and may look brown or grey.
When to see a doctor
See a doctor within a few days if the child is under six months old, if the fever lasts more than three days, if the symptoms are no better after 10 days, if the mouth ulcers are keeping the child from eating and drinking, if the child's immune system is weakened, or if you are pregnant and have been in close contact.
Causes
The illness is caused by a group of viruses that live in the gut and the throat. Children under five are most often affected, partly because they are still learning about handwashing and partly because they share toys, cups and close space.
The virus passes from one child to another through droplets from coughs and sneezes, through the fluid inside the blisters, through saliva on shared cups and toys, and through stool on hands after the toilet or a nappy change. A child is most infectious in the first week, but the virus can stay in the stool for some weeks after the child feels well.
Risk factors
- Being under five years old
- Attending a creche, playgroup or nursery
- A brother, sister or classmate with the illness
- Sharing cups, spoons, bottles and toys
- Crowded living or play spaces
- A weakened immune system, which can make the illness more severe
Complications
Complications are uncommon, and most children recover completely.
- Dehydration, the commonest problem, because the mouth ulcers make drinking painful
- Loss of fingernails or toenails some weeks later, which grow back on their own
- Viral meningitis, uncommon, which may need hospital care
- Inflammation of the brain or weakness of a limb, which are very rare
- Illness in a newborn if the mother catches it close to delivery, which is usually mild
Prevention
- Washing hands with soap after the toilet, after nappy changes and before food
- Teaching children to cough and sneeze into a tissue or the elbow
- Cleaning toys, door handles and surfaces that are touched often
- Not sharing cups, bottles, spoons, towels or bedding
- Keeping a child at home while they are unwell
- Washing soiled clothes and bedding separately on a hot wash
- Avoiding close contact with an affected child during pregnancy
Diagnosis
The diagnosis is made by looking. The combination of fever, sore mouth ulcers and a rash on the palms and soles in a young child is distinctive, and the doctor will also ask whether the illness is going round the creche or school.
Tests are rarely needed. A swab from the throat or a stool sample can identify the virus, and may be used in an outbreak or when a child is unusually unwell, but they do not change the treatment.
Treatment
There is no medicine that clears the virus, and none is needed. The illness settles on its own, and everything done is to keep the child comfortable and drinking.
Cool drinks such as water or milk are soothing, while fruit juice and fizzy drinks sting the ulcers. Soft, cool food such as curd, custard and mashed rice is easier than hot, salty or spicy food. Paracetamol or ibuprofen can be given for fever and for the pain of the ulcers, at the dose advised for the child's age and weight. Aspirin should not be given to children. A pharmacist can suggest a mouth gel, spray or mouthwash suitable for the child's age.
do not work against this virus. A child who becomes dehydrated because the mouth is too sore to drink may need fluids in hospital, which is the main reason a child with this illness is admitted.
Myths and facts
Things people often say about this. Open each one to see what is true.
Myth“An antibiotic will clear it up faster.”What is true?
Fact
It is caused by viruses, and antibiotics do not work against viruses. Treatment is for comfort: cool drinks, soft food and, if the child is in pain or feverish, paracetamol or ibuprofen at the dose advised for their age.
Myth“Once a child has had it, they cannot get it again.”What is true?
Fact
You can get it more than once. Several different viruses cause the illness, so a child who had it last year can catch it again from a different one.
Myth“The child must stay at home until every blister has healed.”What is true?
Fact
NHS advice is to keep a child at home while they are unwell and let them go back once they are feeling better, without waiting for the blisters to clear. CDC advice is similar: a child can return once the fever has gone and they are able to take part normally. Careful handwashing at home and at school matters more than counting blisters.
Myth“Aspirin is a good painkiller for the fever and the mouth ulcers.”What is true?
Fact
Aspirin should not be given to children. Paracetamol or ibuprofen is used instead for fever and for the pain of the ulcers, at the dose advised for the child's age and weight. A pharmacist can also suggest a mouth gel, spray or mouthwash suitable for the child's age.
Questions to ask your doctor
Tick the ones you want answered and take them with you.
Common questions
How do I get my child to drink when the mouth is so sore?
Offer small amounts often rather than a full cup, and keep drinks cool. Milk, water and thin curd drinks are gentler than juice or fizzy drinks, which sting. Ice lollies and cold curd help some children. Giving paracetamol or ibuprofen about half an hour before a drink or a meal can make it easier.
Can adults catch it from the children?
Yes, although it is much less common and adults often have mild symptoms or none at all. They can still pass the virus on. Handwashing after nappy changes and not sharing cups or spoons are the practical steps for the rest of the family.
My child's nails came off a few weeks later. Should I worry?
Losing a fingernail or toenail some weeks after hand, foot and mouth disease is an uncommon but recognised after-effect. It is not painful in most children and the nails grow back on their own without treatment. Mention it to the doctor if the skin around the nail looks red, swollen or infected.
I am pregnant and my child has it. What should I do?
Most infections in pregnancy cause no problems, but it is worth telling your doctor or midwife. Avoid close contact where you can, wash your hands after nappy changes and do not share cups or cutlery. Infection close to the time of delivery can cause a mild illness in the newborn, so the maternity team will want to know.

